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Pgrn.ca Login

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Category P
Domain name pgrn.ca
IP 204.209.20.31
Country by IP CA
Web server type Apache
Hostname ws1.techweavers.net
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Welcome to Problem Gambling Resources Network Alberta

Problem gamblers come from all segments of the population, live in all regions of the province and include men and women of all ages and all socio-economic backgrounds. In addition to gambling for entertainment or fun, people with gambling problems will often gamble alone, chase losses and gamble to escape from problems. Visit website

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Government Resources - pgrn.ca

The Problem Gambling Resources Network (PGRN) is a leader in providing problem gambling awareness, education, prevention, advocacy and treatment referrals within the Edmonton region. The PGRN offers 1 to 2 hour presentations aimed at promoting awareness about how gambling can impact the community & individuals. Visit website

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Can You Help? - pgrn.ca

The Problem Gambling Resources Network (PGRN) is a leader in providing problem gambling awareness, education, prevention, advocacy and treatment referrals within the Edmonton region. The PGRN offers 1 to 2 hour presentations aimed at promoting awareness about how gambling can impact the community & individuals. Visit website

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Help in Alberta - pgrn.ca

The majority of the regional offices of Alberta Health Services offer programs to assist problem gamblers.For more information and to find an addiction services office near you, please call their 24-hour Help Line at 1-866-332-2322.; Northern Addictions Centre Grande Prairie Ablerta offers two services to individuals who are experiencing significat negative impacts in their lives … Visit website

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Pharmacogenomics Global Research Network - Home

The mission of the Pharmacogenomics Global Research Network is to catalyze and lead research in precision medicine for the discovery and translation of genomic variation influencing therapeutic and adverse drug effects. To accomplish this, We will: Promote research and implementation in pharmacogenomics; Provide a forum for collaboration ... Visit website

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Progranulin as a therapeutic target in neurodegenerative …

Progranulin (PGRN, encoded by the GRN gene) plays a key role in the development, survival, function, and maintenance of neurons and microglia in the mammalian brain. It regulates lysosomal biogenesis, inflammation, repair, stress response, and aging. ... 2 Alector, Inc., South San Francisco, CA 94080, USA. Electronic address: ar@alector.com ... Visit website

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Pharmacogenomics Global Research Network - What is PGRN?

A new PGRN, PGRN IV, established July 1, 2015, represents a continuation of these research activities, however in a new model. This new model invites participation of all investigators with an interest in pharmacogenomics research to be part of the new network. Visit website

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New Pharmacogenomics Research Network - PMC

The Pharmacogenomics Research Network (PGRN), which is coordinated by the PGRN-Hub (see pgrn.org), has adopted a new approach to sponsor activities and develop shared resources to enhance research in pharmacogenomics. The PGRN is community-driven and is open to all scientists, where participating researchers’ needs drive its activities. Visit website

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Processing of progranulin into granulins involves multiple …

Background: Progranulin loss-of-function mutations are linked to frontotemporal lobar degeneration with TDP-43 positive inclusions (FTLD-TDP-Pgrn). Progranulin (PGRN) is an intracellular and secreted pro-protein that is proteolytically cleaved into individual granulin peptides, which are increasingly thought to contribute to FTLD-TDP-Pgrn disease … Visit website

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Committees - PGRN

Communications Committee. Mission Statement: To increase the visibility and growth of the PGRN in the scientific and medical communities, through social media and media sharing networks, blogs, pgrn.org and other potential networking opportunities. Chair: Sook Wah Yee. Co-Chair: Mohamed Shahin. Members: Meghan Arwood. Visit website

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Rescue of a lysosomal storage disorder caused by Grn loss of …

Affiliations 1 Denali Therapeutics, South San Francisco, CA, USA.; 2 Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA; On behalf of the ALLFTD investigators.; 3 On behalf of the ALLFTD investigators; Department of Neurology, College of Medicine, Mayo Clinic, … Visit website

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Trehalose upregulates progranulin expression in human and …

Progranulin (PGRN) is a secreted growth factor important for neuronal survival and may do so, in part, by regulating lysosome homeostasis. ... CA). iPSC-neurons were fixed with 4 % paraformaldehyde for 15 min. Cells were then permeabilized with ice-cold methanol or 0.1 % triton X-100 in PBS for 10 min. After blocking with 0.1 % BSA or 5 % ... Visit website

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Treating neurodegenerative diseases with progranulin (pgrn)

CA-2712276-A1 chemical patent summary. Visit website

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Global Public Relations Firms - International PR Firm, PRGN

Global Public Relations Firms - PRGN world’s local public relations agency provides customized communication solutions that combine the scale and stature of an international PR firm with the deep insights and hands-on, senior-level service of a local agency. Check out the top Global Public Relations Firms & Influencer Marketing Agencies. Visit website

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The promotion of bone healing by progranulin, a downstream …

The parameters of micro CT, including BV/TV, Tb.Th and Tb.N, were analyzed, and results indicated that deficiency of PGRN significantly suppressed new bone formation induced by BMP-2, while recombinant PGRN can partially restore the new bone quality in PGRN−/− mice (n=6, p<0.05) (Fig. 5C, 5D and 5E). In addition, the samples from each group ... Visit website

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Pro-cathepsin D, Prosaposin, and Progranulin: Lysosomal …

Pro-CTSD, PSAP, and PGRN Network (PPPN) Proteins Interact with and Help Activate Each Other within the Lysosome. (A) Interaction between Prosaposin (PSAP) and Progranulin (PGRN) amplifies their response. Left: in the nonstressed state PSAP is transported to the endosome/lysosome via mannose-6-phosphate receptor (M6PR) and secreted PGRN is ... Visit website

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PGRN haploinsufficiency increased Wnt5a signaling in ... - PubMed

Here we report that PGRN haploinsufficiency activates the extracellular signal-regulated protein kinases 1 and 2 pathway in a Ca(2+), protein kinase C-dependent, and pertussis toxin-sensitive manner. Addition of exogenous PGRN or conditioned medium from control cells normalized the response of PGRN-deficient lymphoblasts to serum activation. Visit website

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Utility of progranulin and serum leukocyte protease inhibitor as ...

PGRN levels were not significantly increased in patients with early-stage or late-stage EOC as a whole, but an increase in PGRN levels was associated with decreased overall survival in advanced EOC. Conclusions: SLPI levels are elevated in EOC, and SLPI shows promise as a diagnostic biomarker for patients with both elevated and normal CA-125 ... Visit website

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PGRN acts as a novel regulator of mitochondrial homeostasis by ...

Mitochondrial dysfunction is considered as a key mediator in the pathogenesis of diabetic nephropathy (DN). Therapeutic strategies targeting mitochondrial dysfunction hold considerable promise for the treatment of DN. In this study, we investigated the role of progranulin (PGRN), a secreted glycopro … Visit website

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Problem Gambling Resources Network - 211 Alberta

info@pgrn.ca Fees Fee: No Fee Reduction: No Membership Fee: Yes, Contact for details. Accessibility Wheelchair access: Yes - Second floor is not wheelchair accessible.Other disabled access: No - Legal Status Registered Not-For-Profit Topic(s) Mental Health / Addictions - Addiction Support Groups; Visit website

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Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP …

Mutations in the progranulin (PGRN) gene cause a tau pathology-negative and TDP43 pathology-positive form of frontotemporal lobar degeneration (FTLD-TDP).We generated a knock-in mouse harboring the R504X mutation (PGRN-KI). Phosphoproteomic analysis of this model revealed activation of signaling pathways connecting PKC and MAPK to tau prior to … Visit website

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PGRN - Presentations

The PGRN offers 1 to 2 hour presentations aimed at promoting awareness about how gambling can impact the community & individuals. "Adolescent Gambling and Problem Gambling in Alberta" addresses gambling among young people while the "Community & Workplace Presentation" discusses problem gambling as an addiction and targets adults in the workplace, treatment … Visit website

Pgrn.ca Login Guide

Pgrn.ca Login Requirements

  • Pgrn.ca login page link (you can find on this page above);
  • pgrn.ca login correct username, password, or email if necessary;
  • Internet browser, which will open the pgrn.ca login page, if the page does not open, please use a VPN.

How to Login in pgrn.ca? 4 Easy Steps:

  1. Open your browser and follow one of the official pgrn.ca links above.
  2. On the page, find the "Login" button, usually located at the top right of the screen.
  3. The page will ask you to enter your pgrn.ca account and password in the appropriate fields. Sometimes you will need to enter an email address instead of an account. In rare cases, the site will ask you to pass the captcha, this is done to check if you are a bot or not.
  4. Then press the login button, if you entered your login information correctly, you will be taken to your pgrn.ca profile page. Good luck :)

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