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Category | M |
---|---|
Domain name | myfcaas.co.uk |
IP | 46.23.69.44 |
Country by IP | GB |
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Hostname | webdiversion.uk2.net |
2/88 Vα = MYFCAAS : 3/50 Jα = KLTFG . Reprinted with permission from the Journal of Clinical Investigation (49). The α-chain used to generate the mice described by Homann and Eisenbarth ... Visit website
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2/88 Vα = MYFCAAS : 3/50 Jα = KLTFG . Reprinted with permission from the Journal of Clinical Investigation (49). The α-chain used to generate the mice described by Homann and Eisenbarth ... Visit website
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Type I diabetes mellitus, which develops spontaneously in man (), the NOD mouse (), and the BB rat, is considered a T cell-mediated autoimmune disorder.In the past 2 years, Wegmann and coworkers (3–5) have isolated CD4 + T cells from islets of prediabetic NOD mice.T cell lines were established after stimulation with whole islets and were later discovered to react … Visit website
commentaries 1212 The Journal of Clinical Investigation http://www.jci.org Volume 116 Number 5 May 2006 1. Vazquez-Prado, J., Casas-Gonzalez, P., and Gar-cia-Sainz, J ... Visit website
8-1.1 wegmann trav5d-4*04 / valpha 13 myfcaas k tggnnkltfgqgtvlsvi traj56 ylcass 15 / 12 lgwgd e q y f g p g t r l t v l 2-7 /2.6 12-3.20 wegmann trav5d-4*04 / valpha 13 ki?l s g g s n a k l a f g k g t k l s v k traj42 31 / 14 rlgg 2-5 / 2.5 Visit website
11 MYFCAAS A N S GTYQR FG T GT. 12-1.19 V. a. 10 J. a. 9 T Y L CA ME R S SGYN KLTFGKGT. 12-2.35 V. a. 1J. a. 1 L YFCAA IQ NYNQG KL I FG Q GT. 6-6.4 V. a. 8J. a. 48 L Y Y CA PN Q G GSA KL I FG E GT ... Visit website
12-3.20 trav5d-4*04 traj42 myfcaas k i ggsny kltfgkgt klsvks 8-1.9(LN) TRAV5D-4*04 TRAJ42 MYFCAAS R P GGSNY KLTFGKGT KLSVKS 8-1.1(LN) TRAV5D-4*04 TRAJ56 MYFCAAS K TGGNNKLTFG Q GTVLSVIP Visit website
Europe PMC is an archive of life sciences journal literature. IMMUNE RESPONSE. The modern era of immunology began with the clonal selection theory independently expressed by David W. Talmage and Sir Frank Macfarlane Burnet (1,2).The clonal selection theory postulates that a foreign antigen entering the body binds to one unique antibody selected from an … Visit website
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We propose that the insulin peptide B:9–23 and a conserved TCR motif form an “immuno- logic homunculus” underlying the relatively common targeting of insulin by T cells that, as Visit website
Even though there are numerous autoantigens for type 1 diabetes, current evidence suggests that a single autoantigen, namely insulin, is responsible for the key initiating event in autoimmunity. If a single autoantigen is necessary for triggering the autoimmune process, then antigen-specific therapy to block or delete the immune response against that autoantigen … Visit website
Type I diabetes mellitus, which develops spontaneously in man (), the NOD mouse (), and the BB rat, is considered a T cell-mediated autoimmune disorder.In the past 2 years, Wegmann and coworkers (3–5) have isolated CD4 + T cells from islets of prediabetic NOD mice.T cell lines were established after stimulation with whole islets and were later discovered to react with insulin. Visit website
Toma et al. Recognition of a subregion of human proinsulin by class I-restricted T cells in type 1 diabetic patients PNAS 102:10581, 2005 • Selected 8-11mer peptides of proinsulin Visit website
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Title: PowerPoint Presentation Author: bdc Last modified by: GSE Created Date: 3/14/2002 10:50:08 PM Document presentation format: On-screen Show Company Visit website